DNA integrity in diagnosis of premalignant lesions
نویسندگان
چکیده
منابع مشابه
Advances in the diagnosis of oral premalignant and malignant lesions.
The diagnosis and treatment of oral premalignant lesions and squamous cell carcinoma are currently based on histopathologic features, site of involvement and stage of disease. Recent advances in techniques for detecting lesions and predicting their progression or recurrence are reviewed here. Adjuncts for detection of lesions and selection of biopsy sites include vital tissue staining (with tol...
متن کاملBiopsy and histopathologic diagnosis of oral premalignant and malignant lesions.
Accurate diagnosis of premalignant or malignant oral lesions depends on the quality of the biopsy, adequate clinical information and correct interpretation of the biopsy results. The purpose of this paper is to review the procedures for obtaining appropriate biopsy samples, and the criteria for diagnosing and grading dysplasias. The World Health Organization's description of the architectural a...
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background: many oral squamous cell carcinomas (osccs) arise within regions that previously had premalignant lesion. early diagnosis and prompt treatment of premalignant lesions offers the best hope of improving the prognosis in patients with oscc. exfoliative cytology is a simple and non-invasive diagnostic technique that could be used for early detection of oral premalignant and malignant les...
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Modern molecular methods for precancer diagnosis have expanded the range of detectable disease to a preclinical level and provided material for histopathological correlation. The precancer scenario begins with sporadic acquisition of rare PTEN mutation bearing glands, which are morphologically unremarkable, and progresses to discrete foci of cytologically altered glands, readily visible on rout...
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Premalignant lesions of mucosae urinary bladder are flat, noninvasive lesions of urothelium such as atypical hyperplasia/dysplasia and nonpapillary carcinoma in situ (CIS). The aim of this study was to identify association between premalignant lesions and subsequent invasive carcinoma. The study includes 60 patients with diagnosed noninvasive superficial and invasive bladder tumors. Our examina...
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ژورنال
عنوان ژورنال: Medicina Oral Patología Oral y Cirugia Bucal
سال: 2021
ISSN: 1698-6946
DOI: 10.4317/medoral.24287